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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MLXIPL
All Species:
12.73
Human Site:
T586
Identified Species:
21.54
UniProt:
Q9NP71
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NP71
NP_116569.1
852
93073
T586
R
P
P
P
G
P
A
T
L
A
P
S
R
P
L
Chimpanzee
Pan troglodytes
XP_509441
819
90122
P556
F
P
S
T
A
Q
D
P
L
G
K
G
E
Q
V
Rhesus Macaque
Macaca mulatta
XP_001115131
390
43669
S149
I
C
F
F
L
T
P
S
Q
K
K
E
T
R
S
Dog
Lupus familis
XP_546925
857
93734
T591
R
P
P
P
G
P
A
T
L
A
P
P
R
P
L
Cat
Felis silvestris
Mouse
Mus musculus
Q99MZ3
864
94857
T598
R
P
P
P
G
P
A
T
L
A
P
P
R
S
L
Rat
Rattus norvegicus
Q6AXT8
471
49872
V230
L
P
A
G
P
P
G
V
K
R
P
P
P
P
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001104311
895
97370
Q630
S
Q
E
V
P
V
M
Q
A
G
A
A
P
G
P
Frog
Xenopus laevis
NP_001084764
548
60887
G307
S
S
T
R
L
P
S
G
G
F
F
N
S
T
S
Zebra Danio
Brachydanio rerio
XP_001338503
817
90800
S561
I
L
P
Q
T
Q
K
S
P
Q
L
I
V
P
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_724328
836
92381
S565
H
S
P
K
K
S
A
S
L
P
M
A
V
N
S
Honey Bee
Apis mellifera
XP_394429
1014
115124
L747
T
T
C
S
Q
Q
M
L
L
N
T
N
T
Q
T
Nematode Worm
Caenorhab. elegans
P41846
1009
112841
S648
P
S
P
L
D
I
S
S
L
S
R
L
R
T
S
Sea Urchin
Strong. purpuratus
XP_788672
1338
148936
L1048
P
S
T
Q
A
S
A
L
S
L
A
L
A
S
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LVN1
1266
139556
P818
T
P
A
L
P
T
G
P
L
S
S
G
K
G
R
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
41.6
42.9
87.7
N.A.
81.4
20.8
N.A.
N.A.
51.4
30.9
39.4
N.A.
20
29.5
25.5
21.1
Protein Similarity:
100
55.4
43.9
91.4
N.A.
85.7
29.3
N.A.
N.A.
60.7
41.6
53.5
N.A.
36.5
44.9
41.3
33.5
P-Site Identity:
100
13.3
0
93.3
N.A.
86.6
33.3
N.A.
N.A.
0
6.6
13.3
N.A.
20
6.6
20
6.6
P-Site Similarity:
100
20
6.6
93.3
N.A.
86.6
33.3
N.A.
N.A.
6.6
20
20
N.A.
33.3
13.3
40
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
34
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
15
0
15
0
36
0
8
22
15
15
8
0
0
% A
% Cys:
0
8
8
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
8
0
8
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
8
0
0
0
0
0
0
0
0
8
8
0
0
% E
% Phe:
8
0
8
8
0
0
0
0
0
8
8
0
0
0
0
% F
% Gly:
0
0
0
8
22
0
15
8
8
15
0
15
0
15
0
% G
% His:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
15
0
0
0
0
8
0
0
0
0
0
8
0
0
0
% I
% Lys:
0
0
0
8
8
0
8
0
8
8
15
0
8
0
8
% K
% Leu:
8
8
0
15
15
0
0
15
58
8
8
15
0
0
29
% L
% Met:
0
0
0
0
0
0
15
0
0
0
8
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
8
0
15
0
8
0
% N
% Pro:
15
43
43
22
22
36
8
15
8
8
29
22
15
29
8
% P
% Gln:
0
8
0
15
8
22
0
8
8
8
0
0
0
15
0
% Q
% Arg:
22
0
0
8
0
0
0
0
0
8
8
0
29
8
8
% R
% Ser:
15
29
8
8
0
15
15
29
8
15
8
8
8
15
36
% S
% Thr:
15
8
15
8
8
15
0
22
0
0
8
0
15
15
8
% T
% Val:
0
0
0
8
0
8
0
8
0
0
0
0
15
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _